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Protein Structure

In terms of their chemistry, proteins are chains of amino acids. Proteins are an important ingredient in our diet, and are used by the body to build itself. Biologically, proteins play an important role as the enzymes driving many physiological processes. In essence, proteins are the workers driving all biological processes. The following video clip describes proteins’ chemical structure and explains basic concepts in chemistry.

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Which functional groups are present in all amino acids? Select the right answers

1.

Hydroxyl group

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2.

Carboxyl group

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3.

Amino group

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4.

Carbonyl group

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The various amino acids differ only in their side chains.Correct or incorrect? choose the right answer 

1.

Incorrect

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2.

Correct

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Please select the correct statements regarding protein primary structure. 

1.

The bond that forms between amino acids is termed a hydrogen bond.

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2.

Primary structure is synthesized in the cell from the C-terminus to the N-terminus.

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3.

The bond between amino acids is formed by a condensation reaction with the expulsion of a water molecule.

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4.

The bond that forms between amino acids is termed an amide bond.

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5.

The bond that forms between amino acids is termed a peptide bond.

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Please select the correct statements regarding protein 3D structure.

1.

The tertiary structure is formed by folding of the chain due to formation of amide bonds between amino acids along the chain.

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2.

The two types of folding patterns in protein secondary structure are \alpha helices and \beta sheets.

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3.

The secondary structure is maintained mainly by van der waals bonds. 

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4.

Quaternary structure is possible only in proteins containing more than one peptide chain.

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Here is a schematic structure of a protein, in which some of the segments are numbered. Assign the numbers to the relevant terms.

1. 1
2. 2
3. 3
4. 4
5. 5
1. Hydrogen bond
2. Beta sheet
3. Disulfide bond
4. C-terminus
5. Alpha helix

Which of the following roles are not played by proteins in our body? Select the correct answer

1.

Building of body tissues

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2.

Storage of genetic information

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3.

Transport of substances

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4.

Catalysis of chemical reactions in the body

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5.

Protection from pathogens

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Interactive Video

Protein Structure - an interactive video

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Activity Overview

In this activity the students will watch an explanatory video on the topic of protein structure and will answer questions on the subject. Some of the information required is not included in the video and it is therefore important to study in class prior to this activity about the primary, secondary, tertiary and quaternary structure of proteins.

Terms

proteins, amino acids, primary structure, secondary structure, tertiary structure, quaternary structure, peptide bond, condensation, polypeptide, alpha helix, beta sheet, disulfide bonds, hydrogen bonds, C-terminus, N-terminus

Skills

Knowledge building